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id="ey1uvbiufh" class="bw pl30 pr30 pb30 mb20"> <h1 class="f46 lh58 wbwr pt30 mb30">甲狀腺癌是什么原因?qū)е碌?/h1> <div id="ey1uvbiufh" class="fc9 f24 flex aic lh32 mb10"> <time class="icon-time">2025-04-27</time> <span id="ey1uvbiufh" class="icon-eye ml40"> 2649人瀏覽</span> </div> <div id="ey1uvbiufh" class="detail-content wbwr f32 lh52 pt20 taj"><p>甲狀腺癌的發(fā)生與遺傳、環(huán)境輻射、激素水平異常、慢性炎癥刺激及病理因素相關(guān)，需結(jié)合基因檢測(cè)、影像學(xué)檢查和活檢確診。</p><p><img class="up_image_20111121" src="https://file.bohe.cn/fhfile1/M00/71/D8/o4YBAGgOCIaAU96HAArnvtQ1W-s588.jpg"></p><p>1.遺傳因素占甲狀腺癌風(fēng)險(xiǎn)的5%-10%，RET、BRAF等基因突變與髓樣癌、乳頭狀癌密切相關(guān)。有家族史者建議25歲起每年做頸部超聲，必要時(shí)進(jìn)行RET基因篩查。</p><p>2.電離輻射是明確致病因素，兒童期接受頭頸部放療者患病風(fēng)險(xiǎn)增加12倍。日常需減少CT檢查頻次，乘坐飛機(jī)時(shí)選擇靠走道座位降低宇宙輻射暴露。</p><p><img class="up_image_20111121" src="https://file.bohe.cn/fhfile1/M00/2A/3F/oYYBAGgOCIaAEzTFAAerMA8jS1k118.jpg"></p><p>3.雌激素水平異常促進(jìn)甲狀腺細(xì)胞增殖，女性發(fā)病率是男性的3倍。月經(jīng)不調(diào)或長(zhǎng)期服用避孕藥者應(yīng)每半年檢查T(mén)SH水平，控制豆制品攝入量在每日30克以?xún)?nèi)。</p><p>4.橋本甲狀腺炎患者出現(xiàn)甲狀腺腫時(shí)，癌變風(fēng)險(xiǎn)升高3-5倍。抗TPO抗體陽(yáng)性者需每3個(gè)月復(fù)查超聲，結(jié)節(jié)增長(zhǎng)超過(guò)2毫米需進(jìn)行細(xì)針穿刺。</p><p>5.甲狀腺癌病理類(lèi)型決定治療方案：乳頭狀癌可采用半切術(shù)+碘131治療；濾泡狀癌需全切并監(jiān)測(cè)肺部轉(zhuǎn)移；未分化癌需聯(lián)合放化療，中位生存期約6個(gè)月。</p><p>臨床確診后應(yīng)根據(jù)分期選擇治療方式：T1期結(jié)節(jié)可觀察隨訪，T2期行腺葉切除，T3期以上需全甲狀腺切除+中央?yún)^(qū)淋巴結(jié)清掃。術(shù)后TSH抑制治療需維持0.1-0.5mIU/L，定期監(jiān)測(cè)甲狀腺球蛋白。日常注意避免海帶、紫菜等高碘食物，保證每日150微克硒攝入增強(qiáng)免疫力。</p></div> <div id="ey1uvbiufh" class="f24 fc9 lh40 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